Removes homozygous allelic imbalance (AI) bins that do not overlap with LOH (loss of heterozygosity) segments.
Usage
CleanHomalt(rounded_ai, call_seg)
Arguments
- rounded_ai
Data frame or tibble. AI data, must include columns contig, start, stop, allele1Count, allele2Count.
- call_seg
Data frame or tibble. Segment calls, must include columns chrom, loc.start, loc.end, and MAF.
Value
A data frame of AI bins, with homozygous bins outside LOH regions removed.
Examples
# CleanHomalt(rounded_ai, call_seg)
