Merge Adjacent Copy Number Segments Based on Similarity Criteria

Iteratively merges adjacent rows in a data frame of copy number segments if they meet criteria defined by MergeSegCheck. For merged segments, the segment with the greater number of probes provides the call, segment mean, count, and baseline coverage.

Usage

MergeSegRow(df, mergecov)

Arguments

df

A data frame or tibble of copy number segments, with columns such as Sample, Chromosome, Start, End, Num_Probes, Call, Segment_Mean, etc.

mergecov

Numeric threshold for merging of segment mean value.

Value

A data frame or tibble with merged segments and updated segment information.

Details

This function uses MergeSegCheck to determine if two adjacent segments should be merged.