For each segment, selects the allele combination (major/minor) with the highest MAF likelihood,
with special handling for subclonal events and cases where minor allele is zero.
Usage
SelectCallpersegment(results)
Arguments
- results
A data frame or tibble containing all possible calls for each segment, with columns including:
Segcov, MAF, mu, rho, index, major, minor, ccf,
MAF_likelihood, Bio_diff, maf_ll, cov_diff, etc.
Value
A data frame or tibble with the most likely call per segment, including a log_MAF_likelihood column.
Details
Assigns a minimum likelihood for cases where MAF_likelihood is zero.
If possible subclonal events are present, compares top two likelihoods and may select the second as a subclonal event.
For segments where minor == 0, the call is refined using coverage difference.
